Searchable abstracts of presentations at key conferences in endocrinology

ea0032p502 | Endocrine disruptors | ECE2013

Bisphenol-A modulates proliferation of human breast adenocarcinoma cells (MCF-7) by modulating apoptosis and cyclin-A

Havranek Tomas , Macho Ladislav , Fickova Maria

Endocrine disruptors represent exogenous substances that alter hormonal, reproductive, immune and homeostatic systems. Bisphenol-A (BPA) in the form of polymer is a part of polycarbonates used in plastics, food packing and medical devices. Incomplete BPA polymerization and cleavage of weak chemical bonds result in monomer release/leakage to the foods and beverages. Many studies have associated exposure to BPA with higher incidence of hormone-dependent mammary and prostate carc...